In The Science of Sexuality, Georgia Purdom examines the cultural, scientific, and theological claims surrounding human sexuality and gender identity. Addressing the growing confusion in modern culture, she evaluates whether biological or genetic evidence supports the idea that people are born homosexual or transgender.

Purdom traces the historical development of sexuality research from the 20th century to today, highlighting shifts from psychological theories to modern genetic and biological studies. She carefully reviews key scientific research—including twin studies, genome-wide association studies, hormonal research, and epigenetic models—demonstrating the limitations, inconsistencies, and methodological issues present in many widely cited findings.